Cajun Chicken Alfredo Recipe

Name: Cajun Chicken Alfredo
Prep time: 10 min
Cook time: 35 min
Total time: 30 min
Ingredients: 1.5 pounds boneless chicken breasts; 1 tablespoon Cajun seasoning ((To taste. If using store bought, go easy on the added salt, as most brands have added salt.)); 1.5 teaspoons kosher salt (to taste); 2 tablespoons unsalted butter; 16 ounces fettuccine ((or pasta of choice) ); 2 tablespoons unsalted butter; 8 cloves fresh garlic (minced); 1 cup chicken broth; 1 cup heavy whipping cream; 12 ounces parmesan cheese; 1/2 - 1 tablespoon Cajun seasoning (to taste, and be careful with added salt if your seaosning blend has salt in it. ); 1/4-1/2 teaspoon kosher salt (to taste ); 1 cup reserved pasta water; handful of fresh minced parsley (optional)

Want to spice up pasta night? This Cajun Chicken Alfredo Recipe is a must-try! It's on the dinner table in under an hour, making it perfect for a busy weeknight! Juicy, blackened chicken gets coated in a flavorful Cajun spice blend and served with a creamy homemade alfredo sauce over fettuccine pasta is always satisfying, plus easy to make!

large enameled cast iron skillet with creamy cajun chicken alfredo and fettuccine in the pot, surrounded by parmesan, parsley, garlic, and a baguette.

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We all love an easy dinner, especially when it's creamy cajun chicken alfredo! Making your own at home is easier than you think. Any home cook can master this classic pasta dish. It's loved by the whole family, with just a little bit of a kick.

If you're in the mood for more Cajun-inspired recipes, try our Cajun seafood boil, this New Orleans BBQ Shrimp, this Cajun shrimp and sausage pasta, this crawfish dip, and this Cajun salmon pasta!

In the mood for more delicious pasta? Try this creamy salmon pasta, this lobster pasta, or this lobster ravioli sauce!

❤️Why we love this recipe

A delicious classic. A classic pasta dish that's rich, creamy, and has so much flavor. With just the right amount of kick, it's major comfort food!
Protein packed. The juicy and tender chicken breast adds a protein-rich element to the dish, making it filling and satisfying.
Simple ingredients. This recipe is made with 9 simple ingredients that you probably already have on hand in your pantry and kitchen. Anything you need can be found at your local grocery store.
Quick and easy recipe. Getting a complete meal on the table in under an hour is not an easy task, but this recipe is straight forward and quick to make.

🍝Ingredients

Here are the ingredients we used for this recipe. You can find more information for substitutions below.

Boneless skinless chicken breast. Chicken thighs can also be used.
Cajun seasoning: We use our own Cajun seasoning recipe which is salt-free, so you can be generous with it! If using store-bought, taste before adding extra salt.
Parmesan cheese. Freshly grated. This is important. Pre-shredded bags of cheese don't always melt properly because they have additives in them, so you'll want to grate it yourself, or else you will end up with a lumpy sauce!
Pasta. We'd recommend using fettuccine or linguine pasta.
Pasta water. Liquid gold! Starchy pasta water can help loosen up the noodles if they begin to dry out, and revive a dried-up sauce, turning it back into a creamy sauce. Make sure to save some before draining the pasta.

Visit the recipe card for the full quantities and nutritional information.

✨Substitutions & Variations

Here are a few suggestions on additional flavors to try, or simple variations to this recipe.

Add veggies. To add more vegetables to this dish, cook down tomatoes and/or red bell peppers and onions when starting the sauce. You could also stir in some fresh spinach at the end.
Lighter option. Make a lighter cream sauce made with whole milk or half and half.
Thicker sauce. To thicken the sauce, add some room temperature cream cheese.
Spicier. Add more cayenne pepper, Cajun seasoning, or red pepper flakes.
Gluten free. Feel free to use your favorite gluten-free noodles. However, keep in mind, that you will (more than likely) need to add more parmesan cheese to thicken the sauce! Pasta and pasta water add starch to the sauce that is needed to make the sauce thicken, and otherwise, the pasta may become watery.
Keto friendly. To make this recipe low carb and keto friendly, serve it with a keto friendly pasta of choice, or cooked spaghetti squash, or zucchini noodles.
Use leftover (pre-cooked) chicken. For a super quick and easy meal, you can use leftover chicken, although we want to mention that the flavor won't be quite as good! Make sure to add in extra Cajun seasoning if you go this route!

🔪Prep work

Dry chicken breasts off with paper towels.
Mince garlic.
Grate parmesan cheese.
Preheat a large skillet over medium heat.
Bring a large pot of salted water to a rolling boil for the pasta.
Measure out all remaining ingredients.

📋Instructions

Season the chicken breasts liberally with the Cajun seasoning blend and kosher salt on all sides. (Image 1)

To a hot skillet, add 2 tablespoons of butter. Add chicken, and sear on all sides over medium-high heat, until the internal temperature reaches 165°F with an instant read thermometer (affiliate link), about 5-6 minutes per side. (Image 2)

Once cooked, remove from the skillet and set aside to rest for 5-10 minutes before slicing into pieces. Don't drain any of the drippings from the skillet.

raw chicken seasoned with cajun seasoning and salt.

blackened cajun chicken breasts in a skillet.

Meanwhile, cook the pasta for just a few minutes under the package instructions until it's al dente. Undercooking the pasta will make sure it doesn't get overcooked later, since the noodles will continue to cook in the sauce. *Make sure to save a cup of pasta water to thin the sauce, and for reheating purposes later.

Reduce the heat to medium, and add the rest of the butter, and a little splash of chicken broth to the skillet. Add in the minced garlic. (Image 3)

Cook until fragrant, stirring often for about 1 minute, then, immediately deglaze the pan with the rest of the chicken broth. (Image 4)

enameled cast iron skillet with a little bit of broth and blackening seasonings with butter and garlic.

pouring chicken broth into a skille with seasonings and garlic.

Reduce to low heat. Add in the heavy cream. (Image 5)

Stir in parmesan cheese slowly, adding in small handfuls, stirring to melt before adding the next handful. (Image 6)

Season with the remaining Cajun seasoning, and salt to taste.

pouring cream into a spicy cajun broth in a skillet.

creamy broth with parmesan cheese added in a skilet.

If the sauce is too thin, continue adding Parmesan cheese until it reaches your desired level of thickness.

Add the cooked pasta, and a little bit of pasta water, along with parsley. (Image 7)

Toss to combine, adding more pasta water until the sauce clings to the noodles. (Image 8)

cooked pasta tossed in creamy pasta sauce in a skillet.

Add the chicken pieces back over top, sprinkle with more parsley and freshly grated parmesan. Enjoy!

cajun chicken alfredo served with fettuccine.

✨Tips & tricks

Cook the chicken fresh and season it well for the best flavor. While you can use pre-cooked chicken, the flavor just won't be quite the same.
Cook the pasta until it's al dente (cooked but still firm) to prevent it from becoming mushy. We'd recommend cooking it 1-2 minutes under the package directions. As we mentioned before, the pasta will continue to cook in the sauce.
Heavily salt the pasta water. You want about 2 tablespoons of kosher salt per every 1 pound of pasta. The salt will flavor the noodles!
Reserve some pasta cooking water. It's great for thinning the sauce, and for reviving leftovers the next day.
Taste the sauce as you go and adjust the seasoning as needed to achieve the desired level of saltiness and spiciness. Especially if making this recipe for the first time, you'll want to make sure the taste is to your liking.
To prevent the alfredo sauce from curdling or separating once the heavy cream has been added, be sure to stir it frequently and cook it over low heat. Do not boil it.
Use freshly grated parmesan and add it slowly. Make sure each handful of cheese is melted and incorporated before adding the next. Again, low heat (or even off the heat) is your friend here.
Let the chicken rest for a few minutes before slicing it to help keep the juices inside instead of leaking out.

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More Chicken Pasta Recipes To Try

In the mood for hearty and comforting chicken pasta recipes? Here are a few of our favorites!

💭Frequently Asked Questions

How to store the leftovers?

Store leftovers in the fridge in an airtight container for up to 4 days. Do not freeze.

If possible, keep the sauce separate from the pasta to keep the pasta from absorbing too much liquid.

Reheat gently on the stovetop or in the microwave with a splash of pasta water.

Can I make this recipe ahead of time?

Yes, you can make the chicken and alfredo sauce ahead of time and store them in separate containers in the fridge for up to 4 days.

When you're ready to serve, simply reheat the chicken and sauce and toss them with freshly cooked pasta, and pasta water.

Is this recipe spicy?

The Cajun seasoning adds some heat to the dish, but we wouldn't consider this recipe to be super spicy. The level of heat can be adjusted to your liking by adding more or less seasoning, more red pepper flakes, or cayenne pepper.

More Recipes To Consider

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Note: This recipe was originally published in February 2020, but has been improved and re-photographed. We hope you enjoy the new look!